Systems Biology

Andrew Woehler new leader of BIMSB Technology Platform Microscopy

The MDC welcomes Dr Andrew Woehler, who will establish the new Berlin Institute for Medical Systems Biology (BIMSB) Technology Platform Microscopy from May 1. Andrew will have own research projects and cooperations, but also develop new methods, instrumentation and services for current microscopic technologies (e.g. high-throughput and single-molecule imaging microscopy).

Dr. Markus Landthaler. Photo: David Ausserhofer/MDC

MDC researcher Markus Landthaler receives science prize

The cell regulates the activity of its genes in various ways. The GlaxoSmithKline  Foundation awards Dr. Markus Landthaler of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) for his innovative research about gene regulation. The systems biologist Landthaler wants to understand how proteins bind to and influence the function of the […]

Spot on: the computational genomics summer school

“Outstanding faculty… Amazingly well organized… Great people doing very good work… Extremely interesting, even and especially for a wet-lab biologist” – the participants only had superlatives when describing the 3rd International MDC-BIMSB Summer School, taking place at the Max Delbrück Center for Molecular Medicine (MDC) from 18th until 24th of October. This time, the yearly […]

New level of gene regulation plays a role in cardiovascular diseases

When genes are read at the wrong time or in the wrong place they can cause a disease. Less well known is the extent to which the following step, the translation of the gene transcripts into proteins, is also prone to errors. Now, a team lead by Prof. Norbert Hübner of the MDC in Berlin-Buch […]

A speed-dating service for proteins

Yes, a lot of what they say about proteins is true: they are often promiscuous, and have trouble maintaining long-term attachments… In an experiment or model, two molecules may flirt with each other and look like a couple, but is their interaction really intimate and direct? At the MDC, Erich Wanker is a good person […]

Comprehensive new map helps understanding of gene regulation by microRNAs

All the cells in our bodies, be they nerve or kidney cells, blood or skin cells, carry the same genetic information. And yet they all differ considerably. This is because different genes are transcribed in each cell type. In recent years, scientists have found a new class of molecules, so-called “microRNAs,” that play a crucial […]

A metabolic worldview

The huge quantities of data generated by powerful -omics technologies are providing a much fuller understanding of biological processes, yet our knowledge remains far from comprehensive. One challenge is to combine different types of information into models of complex biochemical pathways, which then have to be integrated into even larger models to show how multiple […]