Nature study shows: Salt reduces lactic acid bacteria in the gut whichs influences immune cells responsible for autoimmune diseases and hypertension. Probiotics ameliorate the symptoms in mice.
Research Highlight @en
Where proteins are localized within a cell is crucial to their proper function, especially in cells like neurons. It affects neuronal development and even learning and memory. A research team led by Marina Chekulaeva has for the first time systematically analyzed how this localization comes about. Their article appeared in Nature Communications.
What role do genes play in egg, milk, and nut allergies? A study published in Nature Communications, led by the Max Delbrück Center for Molecular Medicine (MDC) and Charité – Universitätsmedizin Berlin, has found five genetic risk loci that point to the importance of skin and mucous membrane barriers and the immune system in the development of food allergies.
For many obese people gaining weight is a vicious cycle. Scientists at the MDC have now uncovered a contributing factor: genetic variants linked to obesity cause the brain to produce too much of a protein called Cadm1. The result is a disruption in the regulation of body weight and changes in behavior and metabolism, as reported by Matthew Poy and his colleagues in Nature Neuroscience.
In a technological tour de force, Berlin scientists have created a virtual model of an early fly embryo. Its interactive interface allows researchers to explore the blueprint that underlies development at unprecedented spatial resolution and predict which cells express which genes.
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
A new study in the journal Nature reveals that a small signaling molecule has the ability to cut off the blood supply to tumors. This allows the immune system’s T-cells to indirectly fight cancer.
Oliver Daumke’s lab figures out how the inner membranes of mitochondria “get their groove” and assume the complex shapes they need to carry out crucial cellular functions
Ralph Kettritz’s group discovers a unique mechanism by which white blood cells silence a gene involved in autoimmune diseases.
When oxygen gets scarce, the naked mole-rat throws a metabolic switch to draw energy from fructose rather than glucose.