Disease Research

Mission Control for the body’s salt and water supplies

We’ve all heard it: eating salty foods makes you thirstier. But what sounds like good nutritional advice turns out to be an old-wives’ tale. In a study carried out during a simulated mission to Mars, an international group of scientists has found exactly the opposite to be true. “Cosmonauts” who ate more salt retained more water, weren’t as thirsty, and needed more energy.

ERC funding for two MDC scientists 

Medical imaging has an unavoidable side effect: MRI machines generate heat. Thoralf Niendorf has now been awarded an ERC Advanced grant to turn this feature into a tool to study the role of temperature in animal bodies. A second ERC Advanced Grant goes to Thomas Jentsch, who will explore the functions of ion channels in health and disease.

A cellular system makes the battle against a rare disease personal

Some diseases are untreatable because we lack a model system to fully understand symptoms or test possible drugs. This is the case of mitochondrial disease, a rare condition caused by defects in the “cellular powerhouse.” MDC scientists developed the first human stem-cell based system to find drugs to fight mitochondrial disease.