Clinical Research

Fat cells with insulin receptor marked red and lipid droplets marked white.

Insulin-sensitive fat leads to obesity

SORLA is a protein that influences metabolism in adipose tissue. If there is too much of the molecule, fat cells become overly sensitive to insulin and break down less fat. This new link between SORLA and increases in body weight was discovered by MDC researchers. SORLA was previously known for its role in defending the brain against Alzheimer’s disease.

New foundation at the MDC to support young international scientists

As of 22 February 2016, the Max Delbrück Center for Molecular Medicine (MDC) has been home to the newly created Stiftung Gisela Krebs (SGK), a foundation that aims to assist outstanding young international scientists with their research on muscle stem cells. The foundation’s benefactor, Gisela Krebs, is the sister of Nobel laureate Hans A. Krebs, […]

Jeanette Schulz-Menger becomes President of the global SCMR

Jeanette Schulz-Menger already heads the research group “Cardio-MRT” at the Experimental and Clinical Research Center (ECRC) and the University Clinic for Cardiology on the Charité campus in Buch. In January she acquired yet another prominent position: as President of the Society for Cardiovascular Magnetic Resonance (SCMR), the largest international society bringing together specialists in the […]

Getting under the skin of allergies

MDC scientists working with colleagues at institutions around the world have published a study in Nature Communications that sheds light on the atopic march, an especially severe form of allergic disease progression. The researchers identified seven genetic risk loci for the atopic march. Prof. Young-Ae Lee wears two hats. As a pediatrician, she offers special […]

Neurodermatitis genes influence other allergies

There’s a typical “career” for some allergic people, and it starts very early on the skin: babies develop atopic dermatitis, food allergies may follow, then comes asthma and later on hay fever. A group of scientists led by Ingo Marenholz and Young-Ae Lee at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association […]

Translational research yields new approaches to treatment for rare diseases

Rare diseases – sometimes referred to as “orphan diseases” – get left behind in the development of new treatments because of their low prevalence: because patient numbers are small, clinical studies are difficult to conduct and the pharmaceutical industry has no commercial interest in the issue. What can help here is close cooperation between publicly […]