A Berlin study of patients with early-stage colon cancer shows that DNA repair mechanisms and MACC1 gene activity helps determine prognosis and predict response to chemotherapy.
The Berlin-Nord Study Centre has now recruited half of the 10,000 volunteers for Germany’s largest ever cohort study, the NAKO Health Study. It serves the improvement of prevention, early detection and treatment of widespread diseases.
SORLA is a protein that influences metabolism in adipose tissue. If there is too much of the molecule, fat cells become overly sensitive to insulin and break down less fat. This new link between SORLA and increases in body weight was discovered by MDC researchers. SORLA was previously known for its role in defending the brain against Alzheimer’s disease.
SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA was previously known for its protective role in Alzheimer’s disease.
Fred Luft’s Clinical Journal Club has been a campus institution for 20 years. He painstakingly goes through publications, predigests their contents, prepares slides, and writes up a preview that goes out to the staff of the MDC and Charité.
As of 22 February 2016, the Max Delbrück Center for Molecular Medicine (MDC) has been home to the newly created Stiftung Gisela Krebs (SGK), a foundation that aims to assist outstanding young international scientists with their research on muscle stem cells. The foundation’s benefactor, Gisela Krebs, is the sister of Nobel laureate Hans A. Krebs, […]
Jeanette Schulz-Menger already heads the research group “Cardio-MRT” at the Experimental and Clinical Research Center (ECRC) and the University Clinic for Cardiology on the Charité campus in Buch. In January she acquired yet another prominent position: as President of the Society for Cardiovascular Magnetic Resonance (SCMR), the largest international society bringing together specialists in the […]
MDC scientists working with colleagues at institutions around the world have published a study in Nature Communications that sheds light on the atopic march, an especially severe form of allergic disease progression. The researchers identified seven genetic risk loci for the atopic march. Prof. Young-Ae Lee wears two hats. As a pediatrician, she offers special […]
There’s a typical “career” for some allergic people, and it starts very early on the skin: babies develop atopic dermatitis, food allergies may follow, then comes asthma and later on hay fever. A group of scientists led by Ingo Marenholz and Young-Ae Lee at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association […]
Rare diseases – sometimes referred to as “orphan diseases” – get left behind in the development of new treatments because of their low prevalence: because patient numbers are small, clinical studies are difficult to conduct and the pharmaceutical industry has no commercial interest in the issue. What can help here is close cooperation between publicly […]