Cell Biology

Message transmitters at work

Using a single-molecule microscopy, an international team of researchers has observed live for the first time G protein-coupled receptors that perform critical functions such as mediating the biological effects of hormones. Their findings, published in the science journal Nature, could help in the search for new drugs.

CC-BY-3.0, CSIRO.

Protein quality control in the cell: Waste removal more efficient than expected

Proteins perform so many vital tasks that without them, our bodies wouldn’t function. In producing these molecules cells make a remarkable number of mistakes: about one third of all newly synthesized proteins are defective. A failure to recognize and eliminate them can lead to severe diseases. A team led by Prof. Thomas Sommer at the MDC has now gained new insights into the complex process of protein quality control in the cell.