In mammalian embryos, crucial tissues are produced from a group of cells that are scarce and only exist for a very short time. Now, researchers have deciphered their molecular signature.
Archives for April 2017
The signaling molecule interferon gamma is produced by T-cells and it plays a key role in T-cell therapy. It cuts off the blood supply to tumors, as a new study in the journal Nature reveals.
When oxygen gets scarce, the naked mole-rat throws a metabolic switch to draw energy from fructose rather than glucose.
Prof. Thomas J. Jentsch knows: Results from basic research in biology sometimes can quickly become relevant for medicine. He tells us how this happened with one of his subjects of research.
The aim of over 60 research groups working at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) is to understand the molecular basis of the processes underlying states of health and disease. In some cases, this research requires the use of animals alongside many other types of experiments.
When oxygen runs low in their underground burrows, naked mole rats have a unique method of survival. Their metabolism switches from a glucose-based system, which depends on oxygen, to one that makes use of fructose. For a while this suffices to protect sensitive organs such as the heart and brain.
Measurements with small sample sizes can become ‘statistically significant’ due to the combination of small sample numbers and measurement error. This produces effects that are not present in the system under scrutiny.
We’ve all heard it: eating salty foods makes you thirstier. But what sounds like good nutritional advice turns out to be an old-wives’ tale. In a study carried out during a simulated mission to Mars, an international group of scientists has found exactly the opposite to be true. “Cosmonauts” who ate more salt retained more water, weren’t as thirsty, and needed more energy.
A position paper explains why the Alliance of Science Organiziations supports the March for Science.
A tea strainer is very versatile, even in the lab. It can be used to “harvest” eggs – but what sort of eggs?