Archives for June 2016

Fat cells with insulin receptor marked red and lipid droplets marked white.

Insulin-sensitive fat leads to obesity

SORLA is a protein that influences metabolism in adipose tissue. If there is too much of the molecule, fat cells become overly sensitive to insulin and break down less fat. This new link between SORLA and increases in body weight was discovered by MDC researchers. SORLA was previously known for its role in defending the brain against Alzheimer’s disease.

ARCHES award for MDC researcher: High-resolution maps of genetic modifications

This year’s ARCHES prize goes to systems biologist Jan Philipp Junker of the MDC and Erez Levanon of Bar-Ilan University in Israel. The award, conferred on June 14, 2016, will support a research alliance that will allow certain changes in gene transcripts to be presented in high spatial resolution for the very first time.