Archives for February 2016


Blood vessels sprout under pressure

It is blood pressure that drives the opening of small capillaries during angiogenesis. A team of researchers led by Prof. Holger Gerhardt of the MDC observed the process for the first time and published their findings in Nature Cell Biology. The scientists showed how the pressure exerted by the blood causes the membrane of endothelial […]

Structure of a hantavirus protein as a promising model for drug design

There is no treatment for infection with the dangerous hantavirus. Scientists at the Max Delbrück Center for Molecular Medicine (MDC) have now identified the three-dimensional structure of a hantavirus protein that is essential for replication of the virus. They have published their findings in the journal Cell Reports, providing a blueprint for the design of […]

Gene therapy: T cells target mutations to fight tumors

An international research team from the Max Delbrück Center for Molecular Medicine (MDC) and the Charité (partners in the Berlin Institute of Health, BIH), the Humboldt University Berlin and the University of Chicago has successfully modified immune cells to recognize and specifically target tumor cells in mice. Cancer treatments based on the findings would likely […]

Cartoon: The monotonous fate of a stem cell

Here, we present the first in a series of “Molecular biology cartoons” on topics related to research at the MDC. The theme this time is the way stem cells produce more specialized cells. When a stem cell divides, it produces two daughters – one of which is usually maintained as a stem cell, while the […]

From a rare form of high blood pressure to new approaches to a global epidemic

A mutated, hyperactive enzyme causes life-threatening hypertension in the hereditary disease Bilginturan syndrome. Now, in a paper published in the journal Hypertension, a team of researchers headed by scientists from the Max-Delbrück Center for Molecular Medicine (MDC) shows that the syndrome differs from other blood pressure disorders because it leaves the functions of the heart, the major […]

Precise visualization of myocardial injury

World’s first patient-based cardiac MRI study using 7T MRI In a world-first, researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center for Molecular Medicine (MDC) have performed cardiac MRI imaging using a 7T MRI scanner in a patient-based study. 7T MRI imaging is a powerful new technology that allows high resolution images of […]

Stuck on the school bench

Citizen science: Teachers, pupils and scientists work together to measure sitting behavior in young people We all know that a passive lifestyle is bad for our health – but the precise reasons why remain unclear. A group of scientists from the Max Delbrück Center for Molecular Medicine (MDC) has now teamed up with teachers and […]